Do you still remember when was the last time you used the first row of keys on the keyboard? After DOS has gone, it seems that F1-F12 can be removed from the keyboard. In fact, they can still provide a lot of convenience. Here are some functions that I can think of now:
F1 - Help;
F2 - Rename;
F3 - Find;
F5 - Refresh;
F8 - Enter Safe Mode (the most familiar one);
F10 - Enter BIOS (for some laptops).
Everyone can supplement the rest or check out the article in the link!